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Best Nicotinamide Riboside Boosters: Top NAD Supplement List

Anti-aging supplements and products can completely transform you and your outlook on life. They can make you more confident and comfortable in your skin. NAD+ boosters are a relatively new concept in the anti-aging products market, and these supplements are becoming popular with every passing day.

NAD is an abbreviation for Nicotinamide Adenine Dinucleotide (NAD). The NAD supplements are often targeted at reversing the process of aging at a cellular level, therefore, reinforcing and supporting powerful anti-aging effects throughout your body. These supplements are also popularly known as Nicotinamide Mononucleotide (NMN) or Nicotinamide Riboside (NR) supplements. It is also worth noting that as these NAD+ boosters are becoming increasingly popular, you can find them in almost all major retail stores.

But how do you know which are the best NAD+ boosters and which ones should you consider buying in 2021, right? We feel you, so worry not as our team has researched and compiled the list of Best NAD+ boosters you should consider buying in 2021. We present a list of Best NAD+ Boosters in 2021 and a comprehensive and detailed guide of their functionality. We have done the work for you. We have been able to separate myth from facts and hype from science. If you’ve been eyeing anti-aging products, then look no further as we bring you the best NAD+ Boosters and NR anti-aging supplements available in the market in 2021.

A list of Top NAD+ Supplements in 2021

After spending several hours scavenging the Internet, sampling products, researching ingredients, contacting manufacturers, and going through several lab reports, our team has come up with the best NAD+ supplements for 2021. So rest assured you’re getting the most objective list to help you make an informed decision.

Tru Niagen


One of the best-known NAD+ boosters on our list is Tru Niagen, and we have a good reason for placing it on top. One capsule of Tru Niagen’s NAD+ supplement contains about 500mg of Nicotinamide Riboside (NR). This NAD+ supplement helps to produce cellular energy and promotes the repairing process on a cellular level. If you take one Tru Niagen’s NAD+ capsule per day, then you can improve the NAD+ production in your body by at least 80%. This data is per the studies conducted that used approximately 100mg, 300mg, and 1000mg of Niagen’s NR supplement daily.

If you are to buy Tru Niagen’s NAD+ supplements to assist you in your anti-aging journey, then you can either purchase it in volumes of 300mg or 500mg, as per your body requirements.

Many people would usually take the NAD+ boosters daily to help them achieve their desired results in the anti-aging process, maintaining overall health, wellness, and cellular energy. Depending upon how much dosage your body requires, you can purchase these NAD+ supplements by Tru Niagen in 30 count, 90 count, or 180 count bottles. The more quantity you buy, the more you eventually end up saving long-term. Tru Niagen’s NAD+ supplements are backed by solid scientific proof, so it is safe to say that Tru Niagen is one of the leading NAD+ supplements brands in the market today.

Cymbiotika NMN


NMN by Cymbiotika is another well-known NAD+ booster you should consider buying if you are looking for NAD+ supplements that can aid you in your anti-aging journey. It equips your body with Nicotinamide Mononucleotide (NMN), a direct source for NAD+ and a vital component to help you increase the NAD+ levels in your body. This NAD+ supplement is priced at just under $80 per bottle.

Each capsule of the NMN supplement by Cymbiotika contains NMN and complementary ingredients, such as Apigenin, green tea extract, resveratrol, and green coffee bean. These NMN tablets provide your body with antioxidants and several polyphenols, nutrients, and other precursors necessary to produce the desired results and benefits it claims. If you consistently take Cymbiotika NMN capsules, you can supposedly increase the NAD+ levels in your body. As per the official website of Cymbiotika NMN, the supplements company recommends taking at least two capsules every day to help boost energy revitalization and protect your cells from aging. It also provides you with overall active DNA protection, cognitive health, among other similar beneficial effects.



Elysium has been one of the precursor NAD+ products in the NAD+ booster space. This supplement contains a clinically proven B-vitamin complex which Oxford has licensed to help slow down brain atrophy as you get older. According to one study, the B-vitamin complex present in the supplement helped in slowing grey matter atrophy associated with age, especially in regions of the brain that are related to learning and memory, at least by 86%.

Apart from the unique B-vitamin complex present in the NAD+ booster, Elysium also contains Omega-3 fatty acids, anthocyanins, and antioxidants that help you with enhanced bioavailability. Besides this, the NAD+ supplement also allows you to undertake a biological age test kit to verify further and test the supplement’s effects. Elysian highly recommends that you take at least once daily and then test your age with the biological age test kit before and after taking the supplement to analyze results for yourself better. It is very well-known among the users of this NAD+ supplement that Elysian can help you turn your age clock backward and support your anti-aging process quite effectively.

It’s worth noting that Elysian offers two fundamental NAD+ supplements, which include Matter (targeted at your long-term brain health) and Basis (targeted for your general anti-aging and overall DNA health). What distinguishes this NAD+ supplement brand from others on this list is that Elysian is backed by actual clinical trials conducted on human beings.



The next Nicotinamide Riboside (NR) supplement on our list is RiboGEN that consists of approximately 300 mg of NR per serving. The developers of RiboGEN have claimed that their solution is one of the few that contains the same level of NR purity as is used in medical research and studies.

RiboGEN is a no-nonsense NR supplement that contains about 99.5% of Nicotinamide Riboside (NR) and 0.5% of NAM. The NR present in RiboGEN works the same way as the NR in other NAD+ boosters mentioned on this list. This means it acts as a precursor to the overall NAD production by giving your body the essential ingredients required to produce NAD, which ultimately leads to higher NAD+ levels in your body. This supplement is often linked to improved NAD+ levels in your body.

RiboGEN is priced at $330 per bottle, which comes across as quite expensive for a typical person as most other NAD+ supplements mentioned on our list don’t fall into that price range. However, it is worth the pricing as it offers a total of 300 capsules (300 servings), which is much greater than what other NAD+ supplements usually provide.

Life Extension NAD+ Cell Regenerator


Life Extension NAD+ Cell Regenerator does precisely what it’s named, and that is to help you regenerate your cells by promoting NAD+ production inside your body. Much similar to certain NAD+ booster supplements mentioned here, Life Extension NAD+ Cell Regenerator contains about 300 mg dosage of Niagen NR. What’s perhaps a unique thing about this supplement is that Life Extension has added trans-resveratrol into every dose of the NAD+ supplement, which further helps to increase the production of NAD+ quite effectively within your body.

As per the official website of Life Extension, the NAD+ Cell Regenerator can also help you fight off fatigue and other feelings of tiredness on an intrinsic level, thereby promoting your overall mitochondrial health and supporting the production of youthful energy on a cellular level. It is priced at $45 per bottle, and it is one of the top and better valued NAD+ booster supplements compared with other NAD+ boosters on our list. NR Chloride Powder


Science. bio provides its users one of the most accurate Nicotinamide Riboside (NR) boosters in the market today.’s NR Chloride Powder available for just $30 in 10g jars. As a user, you can mix the powder as per your needs or even add it into your capsule to truly experience the heightened benefits of regulating and boosting your NAD+ production.

Every batch of NR Chloride Powder by Science. bio comes batched and with a lot of code, demonstrating publicly visible lab reports to maintain transparency, quality, and trust among the people. It may also be noted that the powdered jar is protected against UV rays to ensure less degradation. It means that you get a higher dosage of Nicotinamide Riboside (NR) without actually having to compromise on the quality and worrying about artificial ingredients that many NAD+ solutions come packed within online stores today.

Alive by Science


The next NAD+ booster supplement on our list is called Alive by Science. This supplement brand offers many NAD+ boosters, including unique liposomal gels that function quite differently from other supplements on our list. Alive by Science is best-known for its NAD+ accompanied by Resveratrol LIPO Gel and its NMN that Resveratrol LIPO Gel accompanies. These LIPO gels are priced at $75 and $80 per bottle, respectively, and the gels are designed in a way so that you can use them for sublingual purposes (underneath the tongue) to ensure maximum absorption.

It may be noted that Alive by Science also offers several powdered NMN and NAD products, therefore, allowing you to enjoy the benefits of both NAD+ and NMN booster supplements, all conveniently packaged as capsules. With a range of options for everybody, Alive by Science may be the perfect choice for you as its unique NAD+ supplements can cater to particular anti-aging needs and offers multiple options for people with different tastes and preferences.


The next NAD brand on our list is called Quicksilver Scientific, which offers a trendy NAD+ booster supplement, commonly known as NAD+ Gold. This NAD supplement claims to improve your NAD levels, resulting in healthy aging, cognition, and energy levels. Similar to the Alive by Science NAD+ boosters mentioned above, NAD+ Gold by Quicksilver Scientific also uses liposomal delivery, leading to superior bioavailability. This means that more active ingredients end up being in your blood to help support your anti-aging journey after you consume this booster.

It is effortless to take this NAD+ booster- all you have to do is press two pumps of NAD+ Gold into your mouth and hold it for 30 seconds and after that, swallow it nicely. That’s about it, and you’re done. This NAD+ solution contains forerunners to NAD+ (which also includes NMN) that help boost the NAD+ levels in your body. This formula is priced at just $60 for a highly-powdered liquid tincture, making Quicksilver Scientific one of the top-rated NAD+ booster supplements companies in the NAD+ market space.


HPN Supplements have an NAD+ Booster called NAD3. This booster is advertised as a “fountain of youth.” It delivers about 311 mg of a unique mix solution in each serving. While most NAD+ boosters on our list use either NMN or NR, the HPN supplements have employed a different approach. The supplement company has created a proprietary mixture known as its NAD3 Patent-Pending Formula. It’s worth knowing that this formula contains theacrine, wasabi, and copper nicotinic acid, all of which directly boost your NAD+ levels.

Suppose you choose to take the NAD3 supplement daily. In that case, you can increase the telomerase activity within your body to produce anti-aging effects along with reducing cellular inflammation, activating NRF2 for cell detoxification, and improving your NAD+ for overall mitochondrial function, among other such benefits. Also, it comes with 60 servings at $60, so it’s a win-win for both the company and you. Hence it falls in one of our better-priced categories of NAD+ boosters that you should consider buying in 2021.

Toniq NMN


Toniq NMN has packaged most appealingly for the overall external look of an NMN-based NAD+ supplement on our list. You would most often expect a no-nonsense packaging from a brand that’s envisioned and marketed as a no-nonsense brand such as the Toniq NMN, and it is precisely what it delivers to you. Each bottle of the NMN booster contains 99% of pure NMN that provides your body with the requisite precursor that it needs to produce more NAD+ in your system.

Toniq NMN is a high-quality NMN-based NAD+ booster that offers 60 servings with each bottle, and yet it is priced at just a modest $45 per bottle. As discussed before, you can save more money if you choose to buy a large bottle with a total of 180 capsules. If you continue taking this high-quality NMN booster daily, then you can significantly increase the NAD+ production within your body.

Liftmode NMN


The NMN supplement by Liftmode contains approximately 10g of Nicotinamide Mononucleotide (NMN) per bottle. It’s worth noting that, unlike NR, NMN isn’t a variant of the B3 vitamin. Instead, it is a nucleotide, much similar to NR, produced synthetically and is associated with its anti-aging effects by targeted affecting the NAD+ levels within your body.

Every single jar of Liftmode’s NMN contains 10g of potent NMN, which allows you to customize your dosage as per your needs.

According to the official website of Liftmode, this particular NMN formula created by Liftmode can help promote cellular energy levels, provide regenerative effects, and sharpen the cognitive function that is a part of the aging brain along with delivering other such benefits. Furthermore, Liftmode utilizes a transparent, sealable plastic jar to store its NMN formula to enhance and sustain the NMN booster’s effectiveness, accuracy, and purity.

How did we rank the best NAD+ supplements for 2021?

Every other NAD+ booster available in the market today claims to be the best and the most effective solution. You would see almost every other NAD booster supplement company advertising and selling how their NAD+ booster can help to increase the NAD+ levels in your body while also providing anti-aging benefits. It isn’t easy to filter through so much information that we, as customers, are constantly bombarded with. It isn’t easy to see all these products with eyes of trust. However, you have to leap every once in a while, and how less stressful it can be if you get the guidance, assistance, and well-researched factual information on your screen just at the click of a link.

Well, that is why we are here today, to help you make a better choice. We have compiled the list of Best NAD+ supplements in 2021 that live up to the hype created in the NAD market today. However, to make a list, we have to put these different supplements through the lens of the following distinguishing metrics. So, here goes a look into the factors that we took into consideration while making the list of Best NAD+ supplements for 2021:

Proven Ingredients

By now, you must be well aware that the two most essential ingredients required in boosting your overall NAD+ production are NMN and NR. If you’re to look at our chosen NAD+ supplements list carefully, you will find at least one of the two ingredients mentioned above as the key ingredient in their blend. Both of these ingredients are precursors to the effective production of NAD+ in your body. The more clinically proven ingredients an NAD+ booster has used, the more effective it will be to help you provide desired results, and the higher we ranked it in our list of Best NAD+ supplements for 2021.

Strong dosage

An NAD+ booster, despite containing the right ingredients, can often fall short of providing you the benefits you initially sought because of its weak dosage options. However, after verifying each of the above-mentioned NAD+ supplements for the right ingredients, we made sure we looked for the available dosage options. Only if the NAD+ booster supplement offered a strong dosage did we consider it for our list. So, strong dosage became a determining factor for the list of NAD+ supplements that we’ve incorporated into this list of the Best NAD+ supplements for 2021 that you should consider buying.


Countless times, it has come to our notice that even renowned NAD+ supplement brands sometimes use proprietary solutions or hide the labels they’ve used to manufacture their NAD+ products. However, we didn’t consider the formulas that made it difficult to verify the contents and ingredients of certain NAD+ supplements for this list. We only preferred NAD+ boosters that were transparent and honest about the ingredients and labels of their NAD+ products and allowed us to leave the guesswork at the back of our minds.

Complementary ingredients

Boosting your NAD+ levels isn’t a science that can be quantified. Studies over the years have shown that using turmeric, resveratrol, and other similar ingredients could help to boost your NAD+ levels in specific ways, which is precisely why so many of the NAD+ supplements today, most definitely, if not all, contain some of these ingredients. While compiling this list, we made sure that we looked over the presence of these complementary ingredients in various NAD+ products. However, we did not look negatively upon those NAD+ brands or supplements that did not contain these specific ingredients, subject to other determining factors.

The reputation of the Manufacturer

Most of the people familiar with the NAD+ products and the NAD industry, in general, know that brands such as Elysium, Cymbiotika, and Niagen have been long enough in the industry to have a good reputation and name to themselves and for their brand. They have marked their presence in the industry, making it nearly impossible for people not to put faith in their products. They have delivered the highest quality NAD+ products for years now, which is why the manufacturer’s reputation plays such an important role while making an informed decision about the quality of NAD+ products created by a reputed brand.

It is also worth noting that some of the top and well-rated NAD+ booster brands have also invested in human clinical trials to add more credibility to their brand name. While making this list, we preferred the NAD+ booster supplements and NAD+ brands that possessed an overall good reputation in the NAD industry over those who were marketing any product under the garb of NAD+ supplements to make a few bucks.

Price and Value

This is perhaps the most important determining factor for a customer when deciding or buying a particular advertised NAD+ product or NAD+ supplement. It becomes the single most crucial point that ultimately affects your final decision. While some people may prefer a $30 NAD+ booster, others may seek to purchase a $200 NAD+ booster supplement. Intertwined with pricing comes another critical factor: the value that a particular product can deliver for its price. While we did feature NAD+ boosters across different price ranges for this list of Best NAD+ supplements for 2021, we also considered the value that a said NAD+ booster supplement offered to its users. To ensure that the money you invested in NAD+ boosters doesn’t go futile, we preferred to rank only those NAD+ supplements that offered a good value at each price.

Advertised Benefits

Any company that starts to sell its products massively does exaggerate its benefits to the customers at times. That is a prevalent yet acceptable part of the entire advertising and marketing procedure. However, for this specific list, we were cautious about companies that fluffed the benefits it offered. For example, they will claim that their NAD+ supplement can help you to reverse your age by, if not many, at least 20 years, which is a hollow emotion to sell upon, or they would claim to make you lose 50 lbs in a month if you purchased their NAD+ supplement. As a user, it becomes imperative to differentiate between a product that would deliver the benefits it claims to provide and one that is only used to attract more customers.

To help you make that decision, we only chose the NAD+ supplements for this list of Best NAD+ supplements that did not contain any hollow benefits. We sought honesty and transparency from the brand’s end to make this list, and hence we only included NAD+ companies that were honest in their advertisements.

Human Clinical Trials

A large part of the process while compiling the list for the Best NAD+ supplements for 2021 was the Human clinical trials and how many NAD+ supplements made efforts to conduct one or even more of such tests. Some of the most prominent NAD+ supplements that we have featured on our list of Best NAD+ supplements for 2021 are those that human clinical trials have backed. Some of the best NAD+ companies have invested in conducting human clinical trials to ensure that their NAD+ supplements work as they have advertised and verify errors, if any, to come up with solutions to rectify such issues as they arise. We were aware that the more scientifically proven and supported an NAD+ booster is, the better it will be and the better results it will deliver, which is why we kept human clinical trials as an essential determining factor compiling this list.

Top four benefits of using an NAD+ supplement in 2021

Many people these days are open to trying new concepts and products that could help them improve a particular area of their lifestyle or overall health and well-being. It is not uncommon for people to increasingly choose NAD+ products today than it was ever before as they are becoming more aware and learning about the benefits that these supplements could offer them. A majority of people will only purchase an NAD+ supplement if they are looking for some anti-aging benefits. However, others also check and look out for other uses that these supplements provide.

But how do you identify if an NAD+ supplement is suitable for your individual needs or not? How do you get to know if a particular NAD+ supplement would provide you with certain expected benefits that you thought were ‘standard’ of all NAD+ supplements available in the market today?

Here’s how: we have provided a list of the following four benefits you should look for in an NAD+ supplement if you’re looking to purchase one in 2021. These benefits are non-negotiable, and an excellent NAD+ supplement would often support at least one of these, if not all of the following benefits. These are:

Fights age-related memory loss issues

As you get older, your memory becomes more blurry, and the chances of encountering and living with memory loss get higher. Not to forget that as you age, some of your memory declines naturally as well. By now, you must have become well-aware and familiar with the fact that NAD+ is an essential component in your anti-aging journey as it helps to repair your DNA and resists any neuronal stress that may arise as you go through your day. Studies conducted on large groups of people who have taken an NAD+ supplement have depicted that people who did take the NAD+ boosters were able to retain their memory and observed their recalling power improve with time as they continued taking these supplements.

On the other hand, it was observed that the people who did not actively consume NAD+ boosters weren’t able to fight age-related memory loss issues and, as a result, lost their partial or complete memory of events as they aged. So, the next time you’re ready to buy an NAD+ booster supplement, make sure to check the NAD+ levels present in the formula. And decide for yourself if it would support you in combating age-related memory loss issues. If the answer is yes, only then go ahead and make that purchase.

Weight loss

According to various studies conducted on NAD+ supplements, it has been found that NAD+ boosters often contain ingredients that help you to manage your overall body weight more effectively. It is worth noting that an excellent NAD+ booster combats the effects of a fat-rich diet and thereby makes it easier for you to lose that excess fat or weight that you’ve been trying to lose for some time now. In one such study conducted on mice, it was observed that the mice fed a high-fat diet gained 60% less weight after taking an NR supplement when compared with that of a placebo group. These mice that had taken the NR supplement also demonstrated high energy levels as compared to their counterparts. Based on the findings of many similar studies, we concluded that having an excellent NAD+ supplement can effectively support your weight loss journey, so if you’re one of those looking forward to losing some pounds, then definitely try using an NAD+ booster.

Reverse the Aging effects

The vast majority of people are looking to reverse the effects of aging more than anything else when they look forward to buying an NAD+ supplement. It is worth noting that there hasn’t been a product developed yet that could make you look younger almost instantly. However, if you are diligently taking an NAD+ supplement, then over time, you will see the magic that it can perform for your skin and how effectively it can aid you in your anti-aging journey, making you look more vibrant and youthful, as per several research studies. However, what surprised us were the captivating findings by the researchers in one such study conducted on mice where the researchers provided NAD+ boosters to mice. After a week, they could not determine the difference between the tissues collected from four-month-old mice and tissues collected from two-year-old mice given NAD+ boosters, respectively.

This was when we became confident about the NAD+ boosters being able to reverse the effects of aging. So the next time you are looking for NAD+ supplements, make sure to go through the quantity and purity of NAD+ present in your specific NAD+ booster supplement to analyze better if the said product is a right fit for your needs and if it in any way would be able to support your overall anti-aging process by reversing the effects of aging.

Boosts overall muscle strength and endurance

Different people have different goals and objectives when they look forward to buying an NAD+ supplement. Some people would only buy it for the effects it is going to have on their physical strength or their body. In contrast, others may look for long-term healing-from-the-core kind of benefits, looking to heal from the inside out and uprooting anything that may have been blocking them from blooming into the best version of themselves. No matter what your objective is, there is always something for everyone in an NAD+ supplement. Some people take NAD+ boosters solely to boost their overall exercise performance.

Several studies have shown that taking an NAD+ booster helps to boost your muscle strength and enhances your endurance ability. Some researchers have also found out that increased NAD+ levels in your body can help with your DNA repair process, muscle growth and improve your endurance at the cellular level. So, if you are looking to boost your muscular strength and become more agile in your tolerance levels, then look no further than an NAD+ supplement and purchase a supplement that would cater to your specific needs.

RELATED: Best Liver Supplements – Review of the Supplements That Work

Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.


Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

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